We Offer Standard and Sophisticated PK/ADME Services Customized to Meet your Project Needs
Pharmacokinetic and ADME Studies
- Standard PK
- 1st Pass Metabolism
- Enterohepatic Re-circulation
- Biliary/Renal/Fecal Clearance
Cassette dosing and analysis is available and economical!
Routes of Dosing
- Oral, Intravenous (bolus and continuous), Intraperitoneal, Subcutaneous, Intramuscular, Mini-osmotic pump
Sample Collection
- Simultaneous blood, bile, urine and fecal sampling in conscious, unrestrained rats
- Repeated, small volume blood sampling and fluid replenishment using the Automated Blood Sampler allows for reduction in animal use and minimizes test compound quantity requirement
Species
- Rat and Mouse